Degradation pathways and impurity profiling of the anticancer drug apalutamide by HPLC and LC–MS/MS and separation of impurities using Design of Experiments-Reference-Cited by-同舟云学术

Degradation pathways and impurity profiling of the anticancer drug apalutamide by HPLC and LC–MS/MS and separation of impurities using Design of Experiments

Published:2022-12-02 Issue:2 Volume:37 Page:
ISSN:0269-3879
Container-title:Biomedical Chromatography
language:en
Short-container-title:Biomedical Chromatography

Author:

Lakka Narasimha Swamy¹^ORCID,Kuppan Chandrasekar¹^ORCID,Vadagam Niroja²^ORCID,Reddamoni Sapthagiri Yadav³,Muthusamy Chandru⁴^ORCID

Affiliation:

1. Department of Chemistry, School of Applied Sciences and Humanities VIGNAN'S Foundation for Science, Technology & Research, Vadlamudi Guntur (Dist.) Andhra Pradesh India

2. Department of Chemistry GITAM (Deemed to be University) Hyderabad Telangana India

3. Department of Analytical Research Dr. SLN Laboratories Pvt. Ltd. Hyderabad Telangana India

4. Department of Mathematics, School of Advanced Sciences Vellore Institute of Technology Vellore Tamilnadu India

Publisher

Wiley

Subject

Clinical Biochemistry,Drug Discovery,Pharmacology,Molecular Biology,General Medicine,Biochemistry,Analytical Chemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1002/bmc.5549

Reference36 articles.

1. RP-HPLC-UV Method for Simultaneous Quantification of Second Generation Non-Steroidal Antiandrogens Along with their Active Metabolites in Mice Plasma: Application to a Pharmacokinetic Study

2. Development of forced degradation and stability indicating studies of drugs—A review

3. Quantitative Stability Indicating Bio-analytical Method Development and Validation of Apalutamide - Apalutamide D3 By Using Ultra Performance Liquid Chromatography in Human Plasma

4. R.a. fisher and the development of statistics ‐ a view in his centerary year'. Dublin;Conniffe D.;Journal of the Statistical and Social Inquiry Society of Ireland,1991

5. ERLEADA (apalutamide)‐FDA. (2018).https://www.accessdata.fda.gov/drugsatfda_docs/label/2019/210951s001lbl.pdf

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