From the kitchen to the medicine cabinet: Examples of food products and supplements used for therapeutic intent

Author:

Gura Kathleen M.12ORCID,Chan Alvin34,Zong Wenjing5,Pai Nikhil67,Duro Debora8910

Affiliation:

1. Department of Pharmacy/Division of Gastroenterology, Hepatology, and Nutrition Boston Children's Hospital Boston Massachusetts USA

2. Department of Pediatrics Harvard Medical School Boston Massachusetts USA

3. UCLA Mattel Children's Hospital Los Angeles California USA

4. David Geffen School of Medicine University of California Los Angeles California USA

5. UTSW/Children's Dallas Dallas Texas USA

6. Department of Pediatrics, Faculty of Health Sciences McMaster University Hamilton Ontario Canada

7. Division of Pediatric Gastroenterology & Nutrition McMaster Children's Hospital Hamilton Ontario Canada

8. Pediatric Gastroenterology, Hepatology and Nutrition Salah Foundation Children Hospital at Broward Health Fort Lauderdale Florida USA

9. NOVA Southeastern University Fort Lauderdale Florida USA

10. Florida International University (FIU) Miami Florida USA

Abstract

Abstract“Food as medicine” has existed for centuries as the foundation of health for many cultures around the globe. It is a practice built on the knowledge that food and diet play important roles in disease prevention and management. Foods that claim to have therapeutic properties are often referred to as functional foods. These foods contain a number of nutritional and nonnutritional compounds that can interact with pharmacologically relevant receptors, either directly or indirectly via their metabolites, to regulate cellular biochemical processes. Although opinions are changing, the concept of food as a therapeutic intervention goes against conventional Western medicine. To provide guidance to clinicians interested in using these products, members of the Food as Medicine working group of the Nutrition Committee NASPGHAN, as part of a two‐part review series, have created summaries of several frequently used nutritional products for therapeutic intent (i.e., fermented foods, fiber, and long‐chain omega‐3 fatty acids) that includes indications, doses, and caveats. Gaps in their use in pediatric patients are discussed. Evidence supporting their use for management of gastrointestinal conditions, especially in the pediatric population, is provided when available.

Publisher

Wiley

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