Sulforaphane: A review of its therapeutic potentials, advances in its nanodelivery, recent patents, and clinical trials

Author:

Mangla Bharti1,Javed Shamama2,Sultan Muhammad Hadi2,Kumar Pankaj3,Kohli Kanchan1,Najmi Asim4,Alhazmi Hassan A.45,Al Bratty Mohammed4,Ahsan Waquar4ORCID

Affiliation:

1. Department of Pharmaceutics School of Pharmaceutical Education & Research, Jamia Hamdard New Delhi India

2. Department of Pharmaceutics, College of Pharmacy Jazan University Jazan Saudi Arabia

3. Department of Pharmaceutics Delhi Pharmaceutical Sciences & Research University (DPSRU) New Delhi India

4. Department of Pharmaceutical Chemistry, College of Pharmacy Jazan University Jazan Saudi Arabia

5. Substance Abuse and Toxicology Research Centre Jazan University Jazan Saudi Arabia

Publisher

Wiley

Subject

Pharmacology

Reference113 articles.

1. Nose-to-brain drug delivery: An update on clinical challenges and progress towards approval of anti-Alzheimer drugs

2. Alumkal J.(2017).Sulforaphane in treating patients with recurrent prostate cancer. Retrieved fromhttps://clinicaltrials.gov/ct2/show/NCT01228084

3. American Society of Clinical Oncology. (2018).Angiogenesis and angiogenesis inhibitors to treat cancer. Retrieved fromhttps://www.cancer.net/navigating‐cancer‐care/how‐cancer‐treated/personalized‐and‐targeted‐therapies/angiogenesis‐and‐angiogenesis‐inhibitors‐treat‐cancer.

4. Broccoli-Derived Sulforaphane and Chemoprevention of Prostate Cancer: From Bench to Bedside

5. Sulforaphane exerts its anti-inflammatory effect against amyloid-β peptide via STAT-1 dephosphorylation and activation of Nrf2/HO-1 cascade in human THP-1 macrophages

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