Effects of NT5C2 Germline Variants on 6‐Mecaptopurine Metabolism in Children With Acute Lymphoblastic Leukemia

Author:

Jiang Chuang123,Yang Wenjian2,Moriyama Takaya2,Liu Chengcheng2,Smith Colton2,Yang Wentao2,Qian Maoxiang45,Li Ziping3,Tulstrup Morten6,Schmiegelow Kjeld67,Crews Kristine R.2,Zhang Hui3,Pui Ching‐Hon8,Evans William2,Relling Mary2,Bhatia Smita9,Yang Jun J.2

Affiliation:

1. Department of Hematology & Oncology Shanghai Children’s Medical Center Shanghai Jiao Tong University School of Medicine Shanghai China

2. Department of Pharmaceutical Sciences St. Jude Children’s Research Hospital Memphis Tennessee USA

3. Department of Hematology/Oncology Guangzhou Women and Children’s Medical Center Guangzhou Guangdong China

4. Department of Hematology and Oncology Institute of Pediatrics Children’s Hospital of Fudan University Shanghai China

5. Shanghai Key Laboratory of Medical Epigenetics International Co‐laboratory of Medical Epigenetics and Metabolism Ministry of Science and Technology Institutes of Biomedical Sciences Fudan University Shanghai China

6. Department of Pediatrics and Adolescent Medicine University Hospital Rigshospitalet Copenhagen Denmark

7. Institute of Clinical Medicine Faculty of Medicine University of Copenhagen Copenhagen Denmark

8. Department of Oncology St. Jude Children’s Research Hospital Memphis Tennessee USA

9. Institute for Cancer Outcomes and Survivorship University of Alabama at Birmingham Birmingham Alabama USA

Funder

National Institutes of Health

Publisher

Wiley

Subject

Pharmacology (medical),Pharmacology

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