Prominence of <i>NUDT15</i> genetic variation associated with 6‐mercaptopurine tolerance in a genome‐wide association study of Japanese children with acute lymphoblastic leukaemia-Reference-Cited by-同舟云学术

Prominence of NUDT15 genetic variation associated with 6‐mercaptopurine tolerance in a genome‐wide association study of Japanese children with acute lymphoblastic leukaemia

Published:2022-08-12 Issue:2 Volume:199 Page:260-269
ISSN:0007-1048
Container-title:British Journal of Haematology
language:en
Short-container-title:Br J Haematol

Author:

Tanaka Yoichi¹^ORCID,Urayama Kevin Y.²³^ORCID,Mori Makiko⁴,Arakawa Yuki⁴,Hasegawa Daisuke⁵^ORCID,Noguchi Yasushi⁶,Yanagimachi Masakatsu⁷⁸,Keino Dai⁷⁹,Ota Setsuo¹⁰,Akahane Koshi¹¹,Inukai Takeshi¹¹^ORCID,Hangai Mayumi³,Kawaguchi Takahisa¹²,Takagi Masatoshi¹³^ORCID,Koh Katsuyoshi⁴,Matsuda Fumihiko¹²,Manabe Atsushi¹⁴^ORCID

Affiliation:

1. Division of Medical Safety Sciences National Institute of Health Sciences Kanagawa Japan

2. Graduate School of Public Health St. Luke's International University Tokyo Japan

3. Department of Social Medicine National Center for Child Health and Development Tokyo Japan

4. Department of Hematology/Oncology Saitama Children's Medical Center Saitama Japan

5. Department of Pediatrics St. Luke's International Hospital Tokyo Japan

6. Department of Pediatrics Japanese Red Cross Narita Hospital Chiba Japan

7. Department of Hematology/Oncology, Children's Cancer Center Kanagawa Children's Medical Center Kanagawa Japan

8. Department of Pediatrics Yokohama City University Hospital Kanagawa Japan

9. Department of Pediatrics St. Marianna University Kanagawa Japan

10. Department of Pediatrics Teikyo University Chiba Medical Center Chiba Japan

11. Department of Pediatrics University of Yamanashi Yamanashi Japan

12. Center for Genomic Medicine Kyoto University Kyoto Japan

13. Department of Pediatrics Tokyo Medical and Dental University Tokyo Japan

14. Department of Pediatrics Hokkaido University Hokkaido Japan

Funder

Japan Society for the Promotion of Science

Publisher

Wiley

Subject

Hematology

Link

https://onlinelibrary.wiley.com/doi/pdf/10.1111/bjh.18405

Reference38 articles.

1. Treatment and biology of pediatric acute lymphoblastic leukemia

2. Prognostic Importance of 6-Mercaptopurine Dose Intensity in Acute Lymphoblastic Leukemia

3. Clinical Pharmacogenetics Implementation Consortium Guideline for Thiopurine Dosing Based on TPMT and NUDT 15 Genotypes: 2018 Update

4. Susceptibility to 6-MP toxicity conferred by aNUDT15variant in Japanese children with acute lymphoblastic leukaemia

5. Inherited NUDT15 Variant Is a Genetic Determinant of Mercaptopurine Intolerance in Children With Acute Lymphoblastic Leukemia

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