Inertial Microfluidic Purification of CAR‐T‐Cell Products

Author:

Elsemary Mona T.1ORCID,Maritz Michelle F.2ORCID,Smith Louise E.3,Warkiani Majid4ORCID,Bandara Veronika5ORCID,Napoli Silvana5,Barry Simon C.5,Coombs Justin T.6,Thierry Benjamin2ORCID

Affiliation:

1. Future Industries Institute ARC Centre of Excellence in Convergent Bio‐Nano Science and Technology Cell Therapy Manufacturing Cooperative Research Centre University of South Australia Mawson Lakes Campus Mawson Lakes SA 5095 Australia

2. Future Industries Institute ARC Centre of Excellence in Convergent Bio‐Nano Science and Technology University of South Australia Mawson Lakes Campus Mawson Lakes SA 5095 Australia

3. Future Industries Institute Cell Therapy Manufacturing Cooperative Research Centre University of South Australia Mawson Lakes Campus Mawson Lakes SA 5095 Australia

4. School of Biomedical Engineering University of Technology Sydney, Broadway Ultimo NSW 2007 Australia

5. Women's and Children's Hospital Adelaide SA 5006 Australia

6. Carina Biotech Adelaide SA 5095 Australia

Publisher

Wiley

Subject

General Biochemistry, Genetics and Molecular Biology,Biomedical Engineering,Biomaterials

Reference64 articles.

1. FDA approves first BCMA-targeted CAR-T cell therapy

2. FDA okays second CAR‐T for Kite ”https://www.nature.com/articles/s41587-020-0676-z(accessed: June2020).

3. National Cancer Institute FDA Approves Second CAR T‐Cell Therapy https://www.cancer.gov/news-events/cancer-currentsblog/2017/yescarta-fda-lymphoma(accessed: October2017).

4. S.Nam J.Smith G.Yang Driving the next wave of innovation in CAR T‐cell therapies | McKinsey https://www.mckinsey.com/industries/pharmaceuticals-and-medical-products/our-insights/drivingthe-next-wave-of-innovation-in-car-t-cell-therapies(accessed: July2019).

5. C.Scott CAR T‐Cell Manufacturing: Challenges Remain https://bioprocessintl.com/manufacturing/cell-therapies/challenges-andopportunities-in-car-t-cell-manufacturing/(accessed: July2020).

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