Clinical grade ACE2 as a universal agent to block SARS‐CoV ‐2 variants

Author:

Monteil Vanessa1ORCID,Eaton Brett2,Postnikova Elena2,Murphy Michael2,Braunsfeld Benedict3ORCID,Crozier Ian4,Kricek Franz5,Niederhöfer Janine6,Schwarzböck Alice6,Breid Helene6,Devignot Stephanie1ORCID,Klingström Jonas7ORCID,Thålin Charlotte8,Kellner Max J910,Christ Wanda7,Havervall Sebastian8,Mereiter Stefan9ORCID,Knapp Sylvia11ORCID,Sanchez Jimenez Anna6,Bugajska‐Schretter Agnes6ORCID,Dohnal Alexander6ORCID,Ruf Christine5,Gugenberger Romana6,Hagelkruys Astrid9ORCID,Montserrat Nuria1213ORCID,Kozieradzki Ivona14ORCID,Hasan Ali Omar14ORCID,Stadlmann Johannes15ORCID,Holbrook Michael R2ORCID,Schmaljohn Connie2,Oostenbrink Chris3ORCID,Shoemaker Robert H16ORCID,Mirazimi Ali1ORCID,Wirnsberger Gerald6ORCID,Penninger Josef M914ORCID

Affiliation:

1. Unit of Clinical Microbiology Karolinska Institutet and Karolinska University Hospital Stockholm Sweden

2. NIAID Integrated Research Facility at Fort Detrick (IRF‐Frederick) Frederick Maryland USA

3. Institute for Molecular Modeling and Simulation University of Natural Resources and Life Sciences (BOKU) Vienna Austria

4. Clinical Research Monitoring Program Directorate Frederick National Laboratory for Cancer Research Frederick Maryland USA

5. NBS‐C BioScience & Consulting GmbH Vienna Austria

6. invIOs Vienna Austria

7. Center for Infectious Medicine Department of Medicine Huddinge Karolinska Institutet Stockholm Sweden

8. Department of Clinical Sciences Karolinska Institute Danderyd Hospital Stockholm Sweden

9. Institute of Molecular Biotechnology of the Austrian Academy of Sciences Vienna Austria

10. Vienna BioCenter PhD Program, Doctoral School of the University at Vienna and Medical University of Vienna Vienna Austria

11. Department of Medicine 1, Laboratory of Infection Biology Medical University of Vienna Vienna Austria

12. Pluripotency for Organ Regeneration Institute for Bioengineering of Catalonia (IBEC), The Barcelona Institute of Science and Technology (BIST) Barcelona Spain

13. Catalan Institution for Research and Advanced Studies (ICREA) Barcelona Spain

14. Department of Medical Genetics, Life Sciences Institute University of British Columbia Vancouver Canada

15. Institute of Biochemistry, Department of Chemistry University of Natural resources and Life, Sciences (BOKU) Vienna Austria

16. Chemopreventive Agent Development Research Group, Division of Cancer Prevention National Cancer Institute, National Institutes of Health Bethesda Maryland USA

Funder

Austrian Science Fund

Center for Strategic Scientific Initiatives, National Cancer Institute

Canadian Institutes of Health Research

Innovative Medicines Initiative

Publisher

EMBO

Subject

Molecular Medicine

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