Dual inhibition of the terminal oxidases eradicates antibiotic‐tolerant Mycobacterium tuberculosis

Author:

Lee Bei Shi1,Hards Kiel23,Engelhart Curtis A4,Hasenoehrl Erik J5ORCID,Kalia Nitin P67,Mackenzie Jared S8ORCID,Sviriaeva Ekaterina1,Chong Shi Min Sherilyn19,Manimekalai Malathy Sony S1,Koh Vanessa H1011,Chan John12,Xu Jiayong12,Alonso Sylvie1011,Miller Marvin J13,Steyn Adrie J C814,Grüber Gerhard1,Schnappinger Dirk4,Berney Michael5,Cook Gregory M23,Moraski Garrett C15,Pethe Kevin16ORCID

Affiliation:

1. School of Biological Sciences Nanyang Technological University Singapore Singapore

2. Department of Microbiology and Immunology School of Biomedical Sciences University of Otago Dunedin New Zealand

3. Maurice Wilkins Centre for Molecular Biodiscovery University of Auckland Auckland New Zealand

4. Department of Microbiology and Immunology Weill Cornell Medical College New York NY USA

5. Department of Microbiology and Immunology Albert Einstein College of Medicine Bronx NY USA

6. Lee Kong Chian School of Medicine Nanyang Technological University Singapore Singapore

7. Ramalingaswami Fellow Clinical Microbiology Division CSIR‐IIIM Jammu and Kashmir India

8. Africa Health Research Institute Nelson R. Mandela School of Medicine University of KwaZulu‐Natal Durban South Africa

9. Nanyang Institute of Technology in Health and Medicine Interdisciplinary Graduate School Nanyang Technological University Singapore Singapore

10. Department of Microbiology Yong Loo Lin School of Medicine National University of Singapore Singapore Singapore

11. Infectious Disease Programme Department of Microbiology and Immunology National University of Singapore Singapore Singapore

12. Department of Medicine Albert Einstein College of Medicine Bronx NY USA

13. Department of Chemistry and Biochemistry University of Notre Dame Notre Dame IN USA

14. Department of Microbiology University of Alabama Birmingham AL USA

15. Department of Chemistry and Biochemistry Montana State University Bozeman MT USA

Funder

Royal Society of New Zealand

Publisher

EMBO

Subject

Molecular Medicine

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