A novel mechano‐enzymatic cleavage mechanism underlies transthyretin amyloidogenesis-Reference-Cited by-同舟云学术

A novel mechano‐enzymatic cleavage mechanism underlies transthyretin amyloidogenesis

Published:2015-08-18 Issue:10 Volume:7 Page:1337-1349
ISSN:1757-4676
Container-title:EMBO Molecular Medicine
language:en
Short-container-title:EMBO Mol Med

Author:

Marcoux Julien¹²,Mangione P Patrizia³⁴,Porcari Riccardo³,Degiacomi Matteo T¹,Verona Guglielmo³⁴,Taylor Graham W³,Giorgetti Sofia⁴,Raimondi Sara⁴,Sanglier‐Cianférani Sarah²,Benesch Justin LP¹,Cecconi Ciro⁵⁶,Naqvi Mohsin M⁶,Gillmore Julian D³,Hawkins Philip N³,Stoppini Monica⁴,Robinson Carol V¹,Pepys Mark B³,Bellotti Vittorio³⁴

Affiliation:

1. Department of Chemistry University of Oxford Oxford UK

2. Laboratoire de Spectrométrie de Masse BioOrganique (LSMBO) University of Strasbourg UDS Strasbourg France

3. Wolfson Drug Discovery Unit Centre for Amyloidosis and Acute Phase Proteins Division of Medicine University College London London UK

4. Department of Molecular Medicine Institute of Biochemistry University of Pavia Pavia Italy

5. Institute of Nanoscience S3 Consiglio Nazionale delle Ricerche Modena Italy

6. Department of Physics, Informatics and Mathematics University of Modena and Reggio Emilia Modena Italy

Publisher

EMBO

Subject

Molecular Medicine

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/emmm.201505357

Reference39 articles.

1. The effects of shear flow on protein structure and function

2. Amyloidogenesis in its biological environment: challenging a fundamental issue in protein misfolding diseases

3. Amyloid deposits in transthyretin-derived amyloidosis: cleaved transthyretin is associated with distinct amyloid morphology

4. Repurposing Diflunisal for Familial Amyloid Polyneuropathy

5. Single-Molecule Studies of Protein Folding

Cited by 122 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. CRISPR/Cas9 Gene Editing: A Novel Approach Towards Alzheimer's Disease Treatment;CNS & Neurological Disorders - Drug Targets;2024-12

2. Identification of the interfacial regions in misfolded transthyretin oligomers;Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics;2024-09

3. Clinical and molecular insights into A97S variants in hereditary transthyretin amyloid polyneuropathy in South China;Amyloid;2024-07-31

4. Cryo-EM confirms a common fibril fold in the heart of four patients with ATTRwt amyloidosis;Communications Biology;2024-07-27

5. Distinctive Deposition Patterns of Sporadic Transthyretin-Derived Amyloidosis in the Atria: A Forensic Autopsy-Based Study;International Journal of Molecular Sciences;2024-07-26