Neurofilaments in spinocerebellar ataxia type 3: blood biomarkers at the preataxic and ataxic stage in humans and mice

Author:

Wilke Carlo12ORCID,Haas Eva34,Reetz Kathrin56,Faber Jennifer78,Garcia‐Moreno Hector910,Santana Magda M11,Warrenburg Bart12,Hengel Holger12,Lima Manuela13,Filla Alessandro14,Durr Alexandra15,Melegh Bela16,Masciullo Marcella17,Infante Jon18,Giunti Paola910,Neumann Manuela219,Vries Jeroen20,Pereira de Almeida Luis11ORCID,Rakowicz Maria21,Jacobi Heike822,Schüle Rebecca12,Kaeser Stephan A12,Kuhle Jens23,Klockgether Thomas78,Schöls Ludger12,Barro Christian23,Hübener‐Schmid Jeannette34,Synofzik Matthis12ORCID,Deuschle Christian,Stransky Elke,Brockmann Kathrin,Schulz Jörg B,Baliko Laszlo,Gaalen Judith,Raposo Mafalda,Jeromin Andreas,

Affiliation:

1. Hertie Institute for Clinical Brain Research (HIH) Center of Neurology University of Tübingen Tübingen Germany

2. German Center for Neurodegenerative Diseases (DZNE) University of Tübingen Tübingen Germany

3. Institute of Medical Genetics and Applied Genomics University of Tübingen Tübingen Germany

4. Centre for Rare Diseases University of Tübingen Tübingen Germany

5. Department of Neurology RWTH Aachen University Aachen Germany

6. JARA‐BRAIN Institute Molecular Neuroscience and Neuroimaging Forschungszentrum Jülich RWTH Aachen University Aachen Germany

7. Department of Neurology University Hospital Bonn Bonn Germany

8. German Center for Neurodegenerative Diseases (DZNE) Bonn Germany

9. Ataxia Centre Department of Clinical and Movement Neurosciences UCL Queen Square Institute of Neurology London UK

10. National Hospital for Neurology and Neurosurgery University College London Hospitals NHS Foundation Trust London UK

11. Center for Neuroscience and Cell Biology University of Coimbra Coimbra Portugal

12. Donders Institute for Brain, Cognition, and Behaviour Department of Neurology Radboud University Medical Center Nijmegen The Netherlands

13. Faculdade de Ciências e Tecnologia Universidade dos Açores Ponta Delgada Portugal

14. Department of Neuroscience, and Reproductive and Odontostomatological Sciences Federico II University Naples Naples Italy

15. Sorbonne Université Institut du Cerveau et de la Moelle épinière (ICM) AP‐HP Inserm CNRS University Hospital Pitié‐Salpêtrière Paris France

16. Department of Medical Genetics Szentagothai Research Center University of Pécs Medical School Pécs Hungary

17. Spinal Rehabilitation Lab (SPIRE) IRCCS Fondazione Santa Lucia Rome Italy

18. Service of Neurology University Hospital Marqués de Valdecilla (IDIVAL) University of Cantabria (UC) Centro de Investigación Biomédica en Red de Enfermedades Neurodegenerativas (CIBERNED) Santander Spain

19. Department of Neuropathology University of Tübingen Tübingen Germany

20. Department of Neurology University Medical Centre Groningen University of Groningen Groningen The Netherlands

21. First Department of Neurology Institute of Psychiatry and Neurology Warsaw Poland

22. Department of Neurology University Hospital of Heidelberg Heidelberg Germany

23. Neurology Departments of Medicine, Biomedicine and Clinical Research University Hospital Basel University of Basel Basel Switzerland

Funder

Horizon 2020 Framework Programme

National Ataxia Foundation

Publisher

EMBO

Subject

Molecular Medicine

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