The GPR 120 agonist TUG ‐891 promotes metabolic health by stimulating mitochondrial respiration in brown fat

Author:

Schilperoort Maaike123ORCID,Dam Andrea D23,Hoeke Geerte23,Shabalina Irina G4ORCID,Okolo Anthony5,Hanyaloglu Aylin C5,Dib Lea H6,Mol Isabel M23,Caengprasath Natarin5,Chan Yi‐Wah7,Damak Sami8,Miller Anne Reifel9,Coskun Tamer9,Shimpukade Bharat10,Ulven Trond10,Kooijman Sander23,Rensen Patrick CN23,Christian Mark1ORCID

Affiliation:

1. Division of Biomedical Sciences Warwick Medical School University of Warwick Coventry UK

2. Division of Endocrinology Department of Medicine Leiden University Medical Center Leiden The Netherlands

3. Einthoven Laboratory for Experimental Vascular Medicine Leiden The Netherlands

4. Department of Molecular Biosciences The Wenner‐Gren Institute The Arrhenius Laboratories F3 Stockholm University Stockholm Sweden

5. Department of Surgery and Cancer Institute of Reproductive and Developmental Biology Imperial College London London UK

6. Institute of Cardiovascular Sciences College of Medical and Dental Sciences University of Birmingham Birmingham UK

7. Lymphocyte Development Group MRC London Institute of Medical Sciences Hammersmith Campus Imperial College London London UK

8. Nestlé Research Center Lausanne Switzerland

9. Lilly Research Laboratories Diabetes/Endocrine Department Lilly Corporate Center Indianapolis IN USA

10. Department of Physics, Chemistry and Pharmacy University of Southern Denmark Odense Denmark

Funder

Genesis Research Trust

Strategiske Forskningsråd

Leids Universitair Medisch Centrum

Universiteit Leiden

Hartstichting

Biotechnology and Biological Sciences Research Council

Eli Lilly and Company

Publisher

EMBO

Subject

Molecular Medicine

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