Dihydrofolate reductase and membrane translocation: evolution of a classic experiment
Author:
Affiliation:
1. Department of Chemistry and Biochemistry University of Bern Bern Switzerland
Publisher
EMBO
Subject
Genetics,Molecular Biology,Biochemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.15252/embr.201745692
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1. Binding of a specific ligand inhibits import of a purified precursor protein into mitochondria
2. A 42K outer-membrane protein is a component of the yeast mitochondrial protein import site
3. Import of a DHFR hybrid protein into glycosomes in vivo is not inhibited by the folate-analogue aminopterin.
4. Molecular architecture of the active mitochondrial protein gate
5. The non-canonical mitochondrial inner membrane presequence translocase of trypanosomatids contains two essential rhomboid-like proteins
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