Degradation of WTAP blocks antiviral responses by reducing the m 6 A levels of IRF3 and IFNAR1 mRNA-Reference-Cited by-同舟云学术

Degradation of WTAP blocks antiviral responses by reducing the m 6 A levels of IRF3 and IFNAR1 mRNA

Published:2021-09 Issue:11 Volume:22 Page:
ISSN:1469-221X
Container-title:EMBO reports
language:en
Short-container-title:EMBO Reports

Author:

Ge Yong¹²,Ling Tao¹²,Wang Yao¹³,Jia Xin¹⁴,Xie Xiongmei¹,Chen Rong¹²,Chen Shangwu¹,Yuan Shaochun¹²⁵^ORCID,Xu Anlong¹³^ORCID

Affiliation:

1. Guangdong Province Key Laboratory of Pharmaceutical Functional Genes MOE Key Laboratory of Gene Function and Regulation State Key Laboratory of Biocontrol School of Life Sciences Sun Yat‐Sen University Guangzhou China

2. Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai) Zhuhai China

3. School of Life Sciences Beijing University of Chinese Medicine Beijing China

4. School of Chinese Materia Medica Beijing University of Chinese Medicine Beijing China

5. Laboratory for Marine Biology and Biotechnology Pilot National Laboratory for Marine Science and Technology Qingdao China

Funder

National Natural Science Foundation of China

Guangdong Science and Technology Department

Ministry of Science and Technology of the People's Republic of China

Publisher

EMBO

Subject

Genetics,Molecular Biology,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embr.202052101

Reference52 articles.

1. Interferon target-gene expression and epigenomic signatures in health and disease

2. Role of p38 Protein Kinase in the Ligand-independent Ubiquitination and Down-regulation of the IFNAR1 Chain of Type I Interferon Receptor

3. m6A RNA methylation regulates the fate of endogenous retroviruses

4. WTAP promotes osteosarcoma tumorigenesis by repressing HMBOX1 expression in an m6A-dependent manner

5. Ubiquitination of cGAS by TRAF6 regulates anti-DNA viral innate immune responses

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