Stepwise pluripotency transitions in mouse stem cells
Author:
Affiliation:
1. Department of Pluripotent Stem Cell Biology, Institute of Molecular Embryology and Genetics (IMEG) Kumamoto University Kumamoto Japan
Funder
Japan Society for the Promotion of Science
Publisher
EMBO
Subject
Genetics,Molecular Biology,Biochemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.15252/embr.202255010
Reference159 articles.
1. Otx2 is an intrinsic determinant of the embryonic stem cell state and is required for transition to a stable epiblast stem cell condition
2. Forebrain and midbrain regions are deleted in Otx2−/− mutants due to a defective anterior neuroectoderm specification during gastrulation
3. Loss of the Otx2-Binding Site in the Nanog Promoter Affects the Integrity of Embryonic Stem Cell Subtypes and Specification of Inner Cell Mass-Derived Epiblast
4. Positive and negative signals from mesoderm regulate the expression of mouse Otx2 in ectoderm explants
5. A gene network establishing polarity in the early mouse embryo
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