Lactate jump‐starts mTORC 1 in cancer cells
Author:
Affiliation:
1. Biozentrum University of Basel Basel Switzerland
Publisher
EMBO
Subject
Genetics,Molecular Biology,Biochemistry
Link
https://onlinelibrary.wiley.com/doi/pdf/10.15252/embr.201948302
Reference9 articles.
1. Oncogenic KRAS signaling activates mTORC1 through COUP‐TFII‐mediated lactate production
2. Metabolic Symbiosis and Immunomodulation: How Tumor Cell-Derived Lactate May Disturb Innate and Adaptive Immune Responses
3. Lactate Metabolism in Human Lung Tumors
4. Lactate administration activates the ERK1/2, mTORC1, and AMPK pathways differentially according to skeletal muscle type in mouse
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3. Curcumin analog GO-Y030 inhibits tumor metastasis and glycolysis;The Journal of Biochemistry;2023-09-01
4. HDAC6-G3BP2 promotes lysosomal-TSC2 and suppresses mTORC1 under ETV4 targeting-induced low-lactate stress in non-small cell lung cancer;Oncogene;2023-02-23
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