Oncogenic KRAS signaling activates mTORC1 through COUP‐TFII‐mediated lactate production

Author:

Byun Jun‐Kyu1,Park Mihyang23,Yun Jae Won45,Lee Jaebon6,Kim Jae Sun6,Cho Sung Jin7,Lee You Mie1,Lee In‐Kyu8,Choi Yeon‐Kyung8,Park Keun‐Gyu8ORCID

Affiliation:

1. Research Institute of Pharmaceutical Science College of Pharmacy Kyungpook National University Daegu Korea

2. Department of Biomedical Science Graduate School Kyungpook National University Daegu Korea

3. BK21 Plus KNU Biomedical Convergence Program Kyungpook National University Daegu Korea

4. Department of Laboratory Medicine and Genetics Samsung Medical Center Sungkyunkwan University School of Medicine Seoul Korea

5. Samsung Advanced Institute of Health Science and Technology Sungkyunkwan University Seoul Korea

6. Sungkyunkwan University School of Medicine Seoul Korea

7. New Drug Development Center Daegu‐Gyeongbuk Medical Innovation Foundation Daegu Korea

8. Department of Internal Medicine School of Medicine Kyungpook National University Kyungpook National University Hospital Daegu Korea

Funder

Ministry of Education

Ministry of Health and Welfare

Publisher

EMBO

Subject

Genetics,Molecular Biology,Biochemistry

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