A cAMP signalosome in primary cilia drives gene expression and kidney cyst formation-Reference-Cited by-同舟云学术

A cAMP signalosome in primary cilia drives gene expression and kidney cyst formation

Published:2022-06-13 Issue:8 Volume:23 Page:
ISSN:1469-221X
Container-title:EMBO reports
language:en
Short-container-title:EMBO Reports

Author:

Hansen Jan N¹^ORCID,Kaiser Fabian¹,Leyendecker Philipp¹,Stüven Birthe¹,Krause Jens‐Henning¹,Derakhshandeh Fatemeh¹,Irfan Jaazba²,Sroka Tommy J³^ORCID,Preval Kenley M⁴,Desai Paurav B⁴,Kraut Michael⁵,Theis Heidi⁵,Drews Anna‐Dorothee⁵,De‐Domenico Elena⁵^ORCID,Händler Kristian⁵,Pazour Gregory J⁴^ORCID,Henderson David J P²,Mick David U³^ORCID,Wachten Dagmar¹^ORCID

Affiliation:

1. Institute of Innate Immunity Medical Faculty University of Bonn Bonn Germany

2. Mironid Ltd. SIPBS Glasgow Scotland, UK

3. Center for Molecular Signaling (PZMS) Center of Human and Molecular Biology (ZHMB) Saarland University, School of Medicine Homburg Germany

4. Program in Molecular Medicine University of Massachusetts Chan Medical School, Biotech II Worcester MA USA

5. Precise Platform for Single Cell Genomics and Epigenomics Department of Systems Medicine German Center for Neurogenerative Diseases Bonn Germany

Funder

Deutsche Forschungsgemeinschaft

Boehringer Ingelheim Fonds

Publisher

EMBO

Subject

Genetics,Molecular Biology,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embr.202154315

Reference81 articles.

1. Cellular signalling by primary cilia in development, organ function and disease

2. Smoothened transduces Hedgehog signals via activity-dependent sequestration of PKA catalytic subunits

3. Gpr161 anchoring of PKA consolidates GPCR and cAMP signaling

4. Compartmentalized signalling: spatial regulation of cAMP by the action of compartmentalized phosphodiesterases

5. Primary Cilia and Mammalian Hedgehog Signaling

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