<scp>hnRNP</scp> R negatively regulates transcription by modulating the association of <scp>P‐TEFb</scp> with <scp>7SK</scp> and <scp>BRD4</scp>-Reference-Cited by-同舟云学术

hnRNP R negatively regulates transcription by modulating the association of P‐TEFb with 7SK and BRD4

Published:2022-07-20 Issue:9 Volume:23 Page:
ISSN:1469-221X
Container-title:EMBO reports
language:en
Short-container-title:EMBO Reports

Author:

Ji Changhe¹^ORCID,Deng Chunchu¹^ORCID,Antor Katharina¹,Bischler Thorsten²^ORCID,Schneider Cornelius³,Fischer Utz³^ORCID,Sendtner Michael¹^ORCID,Briese Michael¹^ORCID

Affiliation:

1. Institute of Clinical Neurobiology University Hospital Wuerzburg Wuerzburg Germany

2. Core Unit Systems Medicine University of Wuerzburg Wuerzburg Germany

3. Department of Biochemistry, Theodor Boveri Institute University of Wuerzburg Wuerzburg Germany

Funder

Deutsche Forschungsgemeinschaft

Hermann und Lilly Schilling-Stiftung für Medizinische Forschung

Interdisziplinäres Zentrum für Klinische Forschung, Universitätsklinikum Würzburg

Graduate School of Life Sciences, Julius-Maximilians-Universität Würzburg

Publisher

EMBO

Subject

Genetics,Molecular Biology,Biochemistry

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embr.202255432

Reference43 articles.

1. Search-and-replace genome editing without double-strand breaks or donor DNA

2. The Transcription-Dependent Dissociation of P-TEFb-HEXIM1-7SK RNA Relies upon Formation of hnRNP-7SK RNA Complexes

3. The structure of P-TEFb (CDK9/cyclin T1), its complex with flavopiridol and regulation by phosphorylation

4. BligheK RanaS LewisM(2018)EnhancedVolcano: publication‐ready volcano plots with enhanced colouring and labeling.https://github.com/kevinblighe/EnhancedVolcano

5. hnRNP R and its main interactor, the noncoding RNA 7SK, coregulate the axonal transcriptome of motoneurons

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1. Conserved role of hnRNPL in alternative splicing of epigenetic modifiers enables B cell activation;EMBO Reports;2024-05-14

2. Targeting BRD4 attenuates the stemness and aggressiveness of ameloblastoma;Oral Diseases;2023-10-05

3. HnRNPR strongly represses splicing of a critical exon associated with spinal muscular atrophy through binding to an exonic AU-rich element;Journal of Medical Genetics;2023-05-24

4. Pan‐cancer analysis of the oncogenic role of HNRNPR in human tumors;Cell Biology International;2023-04-19

5. P-TEFb: The master regulator of transcription elongation;Molecular Cell;2023-02