Search-and-replace genome editing without double-strand breaks or donor DNA-Reference-Cited by-同舟云学术

Search-and-replace genome editing without double-strand breaks or donor DNA

Published:2019-10-21 Issue:7785 Volume:576 Page:149-157
ISSN:0028-0836
Container-title:Nature
language:en
Short-container-title:Nature

Author:

Anzalone Andrew V.,Randolph Peyton B.,Davis Jessie R.,Sousa Alexander A.,Koblan Luke W.,Levy Jonathan M.,Chen Peter J.,Wilson Christopher,Newby Gregory A.,Raguram Aditya,Liu David R.

Publisher

Springer Science and Business Media LLC

Subject

Multidisciplinary

Link

http://www.nature.com/articles/s41586-019-1711-4.pdf

Reference47 articles.

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3. Cong, L. et al. Multiplex genome engineering using CRISPR/Cas systems. Science 339, 819–823 (2013).

4. Mali, P. et al. RNA-guided human genome engineering via Cas9. Science 339, 823–826 (2013).

5. Kosicki, M., Tomberg, K. & Bradley, A. Repair of double-strand breaks induced by CRISPR–Cas9 leads to large deletions and complex rearrangements. Nat. Biotechnol. 36, 765–771 (2018).

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