Nitric oxide maintains endothelial redox homeostasis through PKM 2 inhibition-Reference-Cited by-同舟云学术

Nitric oxide maintains endothelial redox homeostasis through PKM 2 inhibition

Published:2019-07-22 Issue:17 Volume:38 Page:
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:EMBO J

Author:

Siragusa Mauro¹²,Thöle Janina¹²,Bibli Sofia‐Iris¹²,Luck Bert¹²,Loot Annemarieke E¹,Silva Kevin¹,Wittig Ilka²³,Heidler Juliana²³,Stingl Heike¹²,Randriamboavonjy Voahanginirina¹²,Kohlstedt Karin¹,Brüne Bernhard⁴,Weigert Andreas⁴,Fisslthaler Beate¹²,Fleming Ingrid¹²^ORCID

Affiliation:

1. Institute for Vascular Signalling Centre for Molecular Medicine Goethe University Frankfurt am Main Germany

2. German Center for Cardiovascular Research (DZHK) Partner site RheinMain Frankfurt am Main Germany

3. Functional Proteomics SFB 815 Core Unit Faculty of Medicine Goethe University Frankfurt am Main Germany

4. Institute of Biochemistry I Faculty of Medicine Goethe University Frankfurt am Main Germany

Funder

Deutsche Forschungsgemeinschaft

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.2018100938

Reference39 articles.

1. Pyruvate Kinase M2: A Potential Target for Regulating Inflammation

2. Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses

3. Shikonin reduces oedema induced by phorbol ester by interfering with IκBα degradation thus inhibiting translocation of NF-κB to the nucleus

4. Endothelial NO synthase phosphorylated at SER635 produces NO without requiring intracellular calcium increase

5. Shikonin and its analogs inhibit cancer cell glycolysis by targeting tumor pyruvate kinase-M2

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