Leucine‐rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER

Leucine‐rich repeat kinase 2 regulates Sec16A at ER exit sites to allow ER –Golgi export

Published:2014-09-08 Issue:20 Volume:33 Page:2314-2331
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:EMBO J

Author:

Cho Hyun Jin¹,Yu Jia¹,Xie Chengsong¹,Rudrabhatla Parvathi²,Chen Xi¹,Wu Junbing¹,Parisiadou Loukia¹,Liu Guoxiang¹,Sun Lixin¹,Ma Bo¹,Ding Jinhui³,Liu Zhihua⁴⁵,Cai Huaibin¹

Affiliation:

1. Transgenics Section Laboratory of Neurogenetics National Institute on Aging National Institutes of Health Bethesda MD USA

2. Laboratory of Neurochemistry and Laboratory of Neurobiology National Institute of Neurological Disorders and Stroke Bethesda MD USA

3. Bioinformatics Core Laboratory of Neurogenetics National Institute on Aging Bethesda MD USA

4. Laboratory of Immunology National Institute of Allergy and Infectious Diseases National Institutes of Health Bethesda MD USA

5. Institute of Biophysics Chinese Academy of Sciences Beijing China

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.201487807

Reference72 articles.

1. LRRK2 regulates autophagic activity and localizes to specific membrane microdomains in a novel human genomic reporter cellular model

2. The ER-Golgi intermediate compartment (ERGIC): in search of its identity and function

3. Endoplasmic Reticulum Export Site Formation and Function in Dendrites

4. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

5. Unbiased screen for interactors of leucine-rich repeat kinase 2 supports a common pathway for sporadic and familial Parkinson disease

Cited by 65 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. SEC16A Variants Predispose to Chronic Pancreatitis by Impairing ER‐to‐Golgi Transport and Inducing ER Stress;Advanced Science;2024-08-09

2. HTRA1-driven detachment of type I collagen from endoplasmic reticulum contributes to myocardial fibrosis in dilated cardiomyopathy;Journal of Translational Medicine;2024-03-22

3. ARL15, a GTPase implicated in rheumatoid arthritis, potentially repositions its truncated N-terminus as a function of guanine nucleotide binding;International Journal of Biological Macromolecules;2024-01

4. DYRK3 enables secretory trafficking by maintaining the liquid-like state of ER exit sites;Developmental Cell;2023-10

5. Deficiency of Perry syndrome-associated p150Glued in midbrain dopaminergic neurons leads to progressive neurodegeneration and endoplasmic reticulum abnormalities;npj Parkinson's Disease;2023-03-07