Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease-Reference-Cited by-同舟云学术

Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

Published:2008-06-29 Issue:8 Volume:40 Page:955-962
ISSN:1061-4036
Container-title:Nature Genetics
language:en
Short-container-title:Nat Genet

Author:

Barrett Jeffrey C, ,Hansoul Sarah,Nicolae Dan L,Cho Judy H,Duerr Richard H,Rioux John D,Brant Steven R,Silverberg Mark S,Taylor Kent D,Barmada M Michael,Bitton Alain,Dassopoulos Themistocles,Datta Lisa Wu,Green Todd,Griffiths Anne M,Kistner Emily O,Murtha Michael T,Regueiro Miguel D,Rotter Jerome I,Schumm L Philip,Steinhart A Hillary,Targan Stephan R,Xavier Ramnik J,Libioulle Cécile,Sandor Cynthia,Lathrop Mark,Belaiche Jacques,Dewit Olivier,Gut Ivo,Heath Simon,Laukens Debby,Mni Myriam,Rutgeerts Paul,Van Gossum André,Zelenika Diana,Franchimont Denis,Hugot Jean-Pierre,de Vos Martine,Vermeire Severine,Louis Edouard,Cardon Lon R,Anderson Carl A,Drummond Hazel,Nimmo Elaine,Ahmad Tariq,Prescott Natalie J,Onnie Clive M,Fisher Sheila A,Marchini Jonathan,Ghori Jilur,Bumpstead Suzannah,Gwilliam Rhian,Tremelling Mark,Deloukas Panos,Mansfield John,Jewell Derek,Satsangi Jack,Mathew Christopher G,Parkes Miles,Georges Michel,Daly Mark J, ,

Publisher

Springer Science and Business Media LLC

Subject

Genetics

Link

http://www.nature.com/articles/ng.175.pdf

Reference50 articles.

1. Mathew, C.G. New links to the pathogenesis of Crohn's disease provided by genome-wide association scans. Nat. Rev. Genet. 9, 9–14 (2008).

2. Hampe, J. et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat. Genet. 39, 207–211 (2007).

3. Parkes, M. et al. Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat. Genet. 39, 830–832 (2007).

4. Rioux, J.D. et al. Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. Nat. Genet. 39, 596–604 (2007).

5. The Wellcome Trust Case-Control Consortium. Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls. Nature 447, 661–678 (2007).

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