ER‐anchored CRTH2 antagonizes collagen biosynthesis and organ fibrosis via binding LARP6

Author:

Zuo Shengkai1,Wang Bei1,Liu Jiao1,Kong Deping1,Cui Hui2,Jia Yaonan3,Wang Chenyao4,Xu Xin1ORCID,Chen Guilin1,Wang Yuanyang1,Yang Linlin5,Zhang Kai6,Ai Ding7,Du Jie8,Shen Yujun1ORCID,Yu Ying1ORCID

Affiliation:

1. Tianjin Key Laboratory of Inflammatory Biology Center for Cardiovascular Diseases Key Laboratory of Immune Microenvironment and Disease (Ministry of Education) Department of Pharmacology The Province and Ministry Co‐sponsored Collaborative Innovation Center for Medical Epigenetics School of Basic Medical Sciences Tianjin Medical University Tianjin China

2. School of Life Science and Technology Shanghai Tech University Shanghai China

3. School of Pharmaceutical Sciences Zhengzhou University Zhengzhou China

4. Department of Inflammation and Immunity Lerner Research Institute Cleveland Clinic Cleveland OH USA

5. Department of Pharmacology School of Basic Medical Sciences Zhengzhou University Zhengzhou China

6. Department of Biochemistry and Molecular Biology School of Basic Medical Sciences Tianjin Medical University Tianjin China

7. Department of Physiology and Pathophysiology School of Basic Medical Sciences Tianjin Medical University Tianjin China

8. Beijing Anzhen Hospital of Capital Medical University and Beijing Institute of Heart Lung and Blood Vessel Diseases Beijing China

Funder

Postdoctoral Research Foundation of China

National Postdoctoral Program for Innovative Talents

Natural Science Foundation of Tianjin City

Ministry of Science and Technology of the People's Republic of China

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

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