Ablation of the stress protease OMA1 protects against heart failure in mice-Reference-Cited by-同舟云学术

Ablation of the stress protease OMA1 protects against heart failure in mice

Published:2018-03-28 Issue:434 Volume:10 Page:
ISSN:1946-6234
Container-title:Science Translational Medicine
language:en
Short-container-title:Sci. Transl. Med.

Author:

Acin-Perez Rebeca¹,Lechuga-Vieco Ana Victoria¹²^ORCID,del Mar Muñoz Maria¹,Nieto-Arellano Rocío¹^ORCID,Torroja Carlos¹^ORCID,Sánchez-Cabo Fátima¹,Jiménez Concepción¹^ORCID,González-Guerra Andrés¹,Carrascoso Isabel¹^ORCID,Benincá Cristiane¹^ORCID,Quiros Pedro M.³⁴^ORCID,López-Otín Carlos³⁴^ORCID,Castellano José María¹⁵,Ruíz-Cabello Jesús¹²⁶^ORCID,Jiménez-Borreguero Luis Jesús¹⁷^ORCID,Enríquez José Antonio¹⁸^ORCID

Affiliation:

1. Centro Nacional de Investigaciones Cardiovasculares Carlos III, Madrid 28029, Spain.

2. Centro de Investigación Biomédica en Red de Enfermedades respiratorias (CIBERES), C/Melchor Fernández-Almagro 3, Madrid 28029, Spain.

3. Departamento de Bioquímica y Biología Molecular, Facultad de Medicina, Instituto Universitario de Oncología, Universidad de Oviedo, Oviedo 33006, Spain.

4. Centro de Investigación Biomédica en Red de Fisiopatología de la Obesidad y Nutrición (CIBERONC), C/Melchor Fernández-Almagro 3, Madrid 28029, Spain.

5. Centro Integral de Enfermedades Cardiovasculares Hospital Universitario Monteprincipe, HM Hospitales, Madrid 28660, Spain.

6. Universidad Complutense de Madrid, Madrid 28606, Spain.

7. Centro de Investigación Biomédica en Red de Enfermedades Cardiovasculares (CIBERCV), Hospital de La Princesa, Madrid 28006, Spain.

8. Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (CIBERFES), C/Melchor Fernández-Almagro 3, Madrid 28029, Spain.

Abstract

Loss of OMA1 protects cardiomyocytes from death in three murine models of heart failure with diverse etiologies.

Funder

Ministerio de Economía y Competitividad

EU ITN

MC-CIG

Publisher

American Association for the Advancement of Science (AAAS)

Subject

General Medicine

Reference51 articles.

1. 2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC) developed with the special contribution of the Heart Failure Association (HFA) of the ESC;Ponikowski P.;Eur. Heart J.,2016

2. 2016 ACC/AHA/HFSA focused update on new pharmacological therapy for heart failure: An update of the 2013 ACCF/AHA guideline for the management of heart failure: A Report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines and the Heart Failure Society of America;Yancy C. W.;J. Am. Coll. Cardiol.,2016

3. The Mitochondrial Calcium Uniporter Selectively Matches Metabolic Output to Acute Contractile Stress in the Heart

4. The Mitochondrial Calcium Uniporter Matches Energetic Supply with Cardiac Workload during Stress and Modulates Permeability Transition

5. Erratum: Corrigendum: The mitochondrial uniporter controls fight or flight heart rate increases

Cited by 71 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. OPA1 mediates cardiac function and metabolism: in silico and in vivo evidence;2024-08-24

2. Effects of High-Intensity Swimming Interval Training on Area, Perimeter, Circularity Index and Phenotype of Cardiac Mitochondrial Ultrastructure in Sprague Dawley Rats;Life;2024-08-06

3. Opa1 processing is dispensable in mouse development but is protective in mitochondrial cardiomyopathy;Science Advances;2024-08-02

4. Is mitochondrial morphology important for cellular physiology?;Trends in Endocrinology & Metabolism;2024-06

5. SIRT6 in Regulation of Mitochondrial Damage and Associated Cardiac Dysfunctions: A Possible Therapeutic Target for CVDs;Cardiovascular Toxicology;2024-04-30