Disulfiram bolsters T‐cell anti‐tumor immunity through direct activation of LCK‐mediated TCR signaling

Author:

Wang Qinlan123ORCID,Zhu Ting4ORCID,Miao Naijun1ORCID,Qu Yingying4,Wang Zhuning1ORCID,Chao Yinong12,Wang Jing1,Wu Wei5,Xu Xinyi5,Xu Chenqi5,Xia Li6,Wang Feng1234ORCID

Affiliation:

1. Center for Immune‐Related Diseases at Shanghai Institute of Immunology Ruijin Hospital Shanghai Jiao Tong University School of Medicine Shanghai China

2. State Key Laboratory of Oncogenes and Related Genes Department of Immunology and Microbiology Shanghai Jiao Tong University School of Medicine Shanghai China

3. Research Center of Translational Medicine Institute of Pediatric infection, Immunity and Intensive Care Medicine Shanghai Children’s Hospital Shanghai Jiao Tong University School of Medicine Shanghai China

4. Translational Medicine Center Shanghai Institute of Immunology Shanghai General Hospital Shanghai Jiao Tong University School of Medicine Shanghai China

5. State Key Laboratory of Molecular Biology Shanghai Institute of Biochemistry and Cell Biology Center for Excellence in Molecular Cell Science Chinese Academy of Sciences University of Chinese Academy of Sciences Shanghai China

6. Core Facility of Basic Medical Sciences Shanghai Jiao Tong University School of Medicine Shanghai China

Funder

National Key Research and Development Program of China

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

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