The cellular modifier MOAG‐4/SERF drives amyloid formation through charge complementation

Author:

Pras Anita1ORCID,Houben Bert23ORCID,Aprile Francesco A4ORCID,Seinstra Renée1ORCID,Gallardo Rodrigo23,Janssen Leen1ORCID,Hogewerf Wytse1,Gallrein Christian5ORCID,De Vleeschouwer Matthias23,Mata‐Cabana Alejandro1ORCID,Koopman Mandy1ORCID,Stroo Esther1,Vries Minke1,Louise Edwards Samantha1ORCID,Kirstein Janine56ORCID,Vendruscolo Michele4ORCID,Falsone Salvatore Fabio7ORCID,Rousseau Frederic23ORCID,Schymkowitz Joost23ORCID,Nollen Ellen A A1ORCID

Affiliation:

1. European Research Institute for the Biology of Ageing University of Groningen University Medical Centre Groningen Groningen The Netherlands

2. VIB‐KU Leuven Center for Brain and Disease Research Leuven Belgium

3. Switch Laboratory Department of Cellular and Molecular Medicine KU Leuven Leuven Belgium

4. Department of Chemistry Centre for Misfolding Diseases University of Cambridge Cambridge UK

5. Department of Molecular Physiology and Cell Biology Leibniz Research Institute for Molecular Pharmacology im Forschungsverbund Berlin e.V. (FMP) Berlin Germany

6. Faculty of Biology & Chemistry University of Bremen Bremen Germany

7. Institute of Pharmaceutical Sciences University of Graz Graz Austria

Funder

Boehringer Ingelheim Fonds

Vlaams Instituut voor Biotechnologie

KU Leuven

Fonds Wetenschappelijk Onderzoek

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

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