Varicella‐Zoster virus ORF9 is an antagonist of the DNA sensor cGAS-Reference-Cited by-同舟云学术

Varicella‐Zoster virus ORF9 is an antagonist of the DNA sensor cGAS

Published:2022-06-07 Issue:14 Volume:41 Page:
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:The EMBO Journal

Author:

Hertzog Jonny¹^ORCID,Zhou Wen²³^ORCID,Fowler Gerissa¹,Rigby Rachel E¹^ORCID,Bridgeman Anne¹,Blest Henry TW¹,Cursi Chiara¹^ORCID,Chauveau Lise¹^ORCID,Davenne Tamara¹,Warner Benjamin E⁴^ORCID,Kinchington Paul R⁴⁵,Kranzusch Philip J²³⁶,Rehwinkel Jan¹^ORCID

Affiliation:

1. MRC Human Immunology Unit MRC Weatherall Institute of Molecular Medicine Radcliffe Department of Medicine University of Oxford Oxford UK

2. Department of Microbiology Harvard Medical School Boston MA USA

3. Department of Cancer Immunology and Virology Dana‐Farber Cancer Institute Boston MA USA

4. Department of Ophthalmology University of Pittsburgh Pittsburgh PA USA

5. Department of Microbiology and Molecular Genetics University of Pittsburgh Pittsburgh PA USA

6. Parker Institute for Cancer Immunotherapy Dana‐Farber Cancer Institute Boston MA USA

Funder

Medical Research Foundation

Wellcome Trust

European Commission

Division of Microbiology and Infectious Diseases, National Institute of Allergy and Infectious Diseases

Health Resources in Action

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.2021109217

Reference88 articles.

1. Varicella-Zoster Virus Infection of Human Dendritic Cells and Transmission to T Cells: Implications for Virus Dissemination in the Host

2. cGAS in action: Expanding roles in immunity and inflammation

3. IFI16 and cGAS cooperate in the activation of STING during DNA sensing in human keratinocytes

4. cGAS senses long and HMGB/TFAM-bound U-turn DNA by forming protein–DNA ladders

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