Discrete <scp>RNA</scp> – <scp>DNA</scp> hybrid cleavage by the <scp>EXD2</scp> exonuclease pinpoints two rate‐limiting steps-Reference-Cited by-同舟云学术

Discrete RNA – DNA hybrid cleavage by the EXD2 exonuclease pinpoints two rate‐limiting steps

Published:2022-11-03 Issue:1 Volume:42 Page:
ISSN:0261-4189
Container-title:The EMBO Journal
language:en
Short-container-title:The EMBO Journal

Author:

Jia Xinshuo¹^ORCID,Li Yanan¹^ORCID,Wang Teng¹,Bi Lulu¹^ORCID,Guo Lijuan¹^ORCID,Chen Ziting¹,Zhang Xia¹,Ye Shasha¹,Chen Jia¹,Yang Bei¹²^ORCID,Sun Bo¹^ORCID

Affiliation:

1. School of Life Science and Technology ShanghaiTech University Shanghai China

2. Shanghai Institute for Advanced Immunochemical Studies ShanghaiTech University Shanghai China

Funder

National Natural Science Foundation of China

Natural Science Foundation of Shanghai

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/embj.2022111703

Reference46 articles.

1. Characterization of DNA structures by circular dichroism;Bishop GR;Curr Protoc Nucleic Acid Chem,2003

2. EXD2 promotes homologous recombination by facilitating DNA end resection

3. Relationship of DNA degradation by Saccharomyces cerevisiae Exonuclease 1 and its stimulation by RPA and Mre11-Rad50-Xrs2 to DNA end resection

4. Exact Solutions for Kinetic Models of Macromolecular Dynamics

5. The mitochondrial outer-membrane location of the EXD2 exonuclease contradicts its direct role in nuclear DNA repair

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