Nuclear ARRB 1 induces pseudohypoxia and cellular metabolism reprogramming in prostate cancer

Author:

Zecchini Vincent1,Madhu Basetti1,Russell Roslin1,Pértega‐Gomes Nelma2,Warren Anne3,Gaude Edoardo4,Borlido Joana1,Stark Rory1,Ireland‐Zecchini Heather1,Rao Roheet1,Scott Helen1,Boren Joan1,Massie Charlie1,Asim Mohammad1,Brindle Kevin1,Griffiths John1,Frezza Christian4,Neal David E1,Mills Ian G56

Affiliation:

1. Department of CRUK CRUK Cambridge Institute University of Cambridge Cambridge UK

2. Life and Health Sciences Research Institute School of Health Sciences University of Minho Braga Portugal

3. Department of Pathology University of Cambridge Cambridge UK

4. Medical Research Council Cancer Cell Unit Hutchison/MRC Research Centre University of Cambridge Cambridge UK

5. Prostate Cancer Research Group Centre for Molecular Medicine Norway (NCMM) Nordic EMBL Partnership University of Oslo and Oslo University Hospital Oslo Norway

6. Department of Cancer Prevention and Urology Institute of Cancer Research and Oslo University Hospital Oslo Norway

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

Reference76 articles.

1. Detection of increased choline compounds with proton nuclear magnetic resonance spectroscopy subsequent to malignant transformation of human prostatic epithelial cells;Ackerstaff E1;Cancer Res,2001

2. Oxygen Sensors at the Crossroad of Metabolism

3. High-Resolution Profiling of Histone Methylations in the Human Genome

4. Controlling the False Discovery Rate: A Practical and Powerful Approach to Multiple Testing

5. Molecular and cellular processes underlying the hallmarks of head and neck cancer

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