Oligomeric interactions maintain active‐site structure in a noncooperative enzyme family

Author:

Li Yaohui12ORCID,Zhang Rongzhen1ORCID,Wang Chi23ORCID,Forouhar Farhad24ORCID,Clarke Oliver B5ORCID,Vorobiev Sergey2ORCID,Singh Shikha2ORCID,Montelione Gaetano T6ORCID,Szyperski Thomas7ORCID,Xu Yan1ORCID,Hunt John F2ORCID

Affiliation:

1. Key Laboratory of Industrial Biotechnology of Ministry of Education and School of Biotechnology Jiangnan University Wuxi China

2. Department of Biological Sciences, 702 Sherman Fairchild Center, MC2434 Columbia University New York NY USA

3. Cryo‐Electron Microscopy Center Columbia University Irving Medical Center New York NY USA

4. Macromolecular Crystallography Shared Resource Herbert Irving Comprehensive Cancer Center Columbia University Irving Medical Center New York NY USA

5. Department of Physiology and Cellular Biophysics and Department of Anesthesiology Columbia University Irving Medical Center New York NY USA

6. Department of Chemistry & Chemical Biology and Center for Biotechnology & Interdisciplinary Sciences Rensselaer Polytechnic Institute Troy NY USA

7. Department of Chemistry State University of New York at Buffalo Buffalo NY USA

Funder

National Key Research and Development Program of China

China Association for Science and Technology

Graduate Research and Innovation Projects of Jiangsu Province

State Administration of Foreign Experts Affairs

Ministry of Education of the People's Republic of China

Office of Extramural Research, National Institutes of Health

Publisher

EMBO

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Molecular Biology,General Neuroscience

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