Nonproductive exposure of PBMCs to SARS‐CoV ‐2 induces cell‐intrinsic innate immune responses

Author:

Kazmierski Julia12ORCID,Friedmann Kirstin1,Postmus Dylan12ORCID,Emanuel Jackson1ORCID,Fischer Cornelius3ORCID,Jansen Jenny12,Richter Anja1,Bosquillon de Jarcy Laure14,Schüler Christiane12,Sohn Madlen3,Sauer Sascha3,Drosten Christian15,Saliba Antoine‐Emmanuel6,Sander Leif Erik4,Müller Marcel A15ORCID,Niemeyer Daniela15ORCID,Goffinet Christine12ORCID

Affiliation:

1. Institute of Virology, Campus Charité Mitte, Charité – Universitätsmedizin Berlin Berlin Germany

2. Berlin Institute of Health Berlin Germany

3. Scientific Genomics Platforms, Laboratory of Functional Genomics, Nutrigenomics and Systems Biology Max Delbrück Center for Molecular Medicine Berlin Germany

4. Department of Infectious Diseases and Respiratory Medicine Charité ‐ Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt‐Universität zu Berlin, and Berlin Institute of Health (BIH) Berlin Germany

5. German Center for Infection Research, Associated Partner Charité Berlin Germany

6. Helmholtz Institute for RNA‐based Infection Research (HIRI) Helmholtz‐Center for Infection Research (HZI) Würzburg Germany

Funder

Berlin Institute of Health

Bundesministerium für Bildung und Forschung

Helmholtz-Gemeinschaft

Bayerisches Staatsministerium für Wissenschaft und Kunst

Publisher

EMBO

Subject

Applied Mathematics,Computational Theory and Mathematics,General Agricultural and Biological Sciences,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Information Systems

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