Aging is associated with increased chromatin accessibility and reduced polymerase pausing in liver-Reference-Cited by-同舟云学术

Aging is associated with increased chromatin accessibility and reduced polymerase pausing in liver

Published:2022-09 Issue:9 Volume:18 Page:
ISSN:1744-4292
Container-title:Molecular Systems Biology
language:en
Short-container-title:Molecular Systems Biology

Author:

Bozukova Mihaela¹,Nikopoulou Chrysa¹^ORCID,Kleinenkuhnen Niklas¹²,Grbavac Dora¹,Goetsch Katrin¹,Tessarz Peter¹³^ORCID

Affiliation:

1. Max Planck Research Group ‘Chromatin and Ageing’ Max Planck Institute for Biology of Ageing Cologne Germany

2. Faculty of Medicine, Institute of Medical Statistics and Computational Biology University of Cologne Cologne Germany

3. Cellular Stress Responses in Aging‐Associated Diseases (CECAD) University of Cologne Cologne Germany

Funder

Max-Planck-Gesellschaft

Publisher

EMBO

Subject

Applied Mathematics,Computational Theory and Mathematics,General Agricultural and Biological Sciences,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Information Systems

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/msb.202211002

Reference83 articles.

1. Promoter-proximal pausing of RNA polymerase II: emerging roles in metazoans

2. NELF Regulates a Promoter-Proximal Step Distinct from RNA Pol II Pause-Release

3. SPT5 stabilization of promoter-proximal RNA polymerase II

4. MYC Recruits SPT5 to RNA Polymerase II to Promote Processive Transcription Elongation

5. Gene activation by metazoan enhancers: Diverse mechanisms stimulate distinct steps of transcription

Cited by 16 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. The activity of early-life gene regulatory elements is hijacked in aging through pervasive AP-1-linked chromatin opening;Cell Metabolism;2024-08

2. Polyploidisation pleiotropically buffers ageing in hepatocytes;Journal of Hepatology;2024-08

3. Genome-wide analysis of hepatic DNA methylation reveals impact of epigenetic aging on xenobiotic metabolism and transport genes in an aged mouse model;GeroScience;2024-04-01

4. SIRT7 regulates NUCKS1 chromatin binding to elicit metabolic and inflammatory gene expression in senescence and liver aging;2024-02-08

5. Changes in microglia chromatin accessibility in aged female mice;2024-01-20