Causal integration of multi‐omics data with prior knowledge to generate mechanistic hypotheses-Reference-Cited by-同舟云学术

Causal integration of multi‐omics data with prior knowledge to generate mechanistic hypotheses

Published:2021-01 Issue:1 Volume:17 Page:
ISSN:1744-4292
Container-title:Molecular Systems Biology
language:en
Short-container-title:Mol Syst Biol

Author:

Dugourd Aurelien¹²³⁴^ORCID,Kuppe Christoph³⁴⁵^ORCID,Sciacovelli Marco⁶^ORCID,Gjerga Enio¹²^ORCID,Gabor Attila¹,Emdal Kristina B.⁷,Vieira Vitor⁸,Bekker‐Jensen Dorte B.⁷,Kranz Jennifer³⁹¹⁰,Bindels Eric.M.J.¹¹,Costa Ana S.H.⁶,Sousa Abel¹²¹³,Beltrao Pedro¹³^ORCID,Rocha Miguel⁸,Olsen Jesper V.⁷^ORCID,Frezza Christian⁶^ORCID,Kramann Rafael³⁴⁵^ORCID,Saez‐Rodriguez Julio¹²¹⁴^ORCID

Affiliation:

1. Faculty of Medicine, and Heidelberg University Hospital Institute for Computational Biomedicine Heidelberg University Heidelberg Germany

2. Faculty of Medicine Joint Research Centre for Computational Biomedicine (JRC‐COMBINE) RWTH Aachen University Aachen Germany

3. Faculty of Medicine Institute of Experimental Medicine and Systems Biology RWTH Aachen University Aachen Germany

4. Division of Nephrology and Clinical Immunology Faculty of Medicine RWTH Aachen University Aachen Germany

5. Department of Internal Medicine, Nephrology and Transplantation Erasmus Medical Center Rotterdam The Netherlands

6. MRC Cancer Unit Hutchison/MRC Research Centre University of Cambridge Cambridge UK

7. Faculty of Health and Medical Sciences Proteomics Program Novo Nordisk Foundation Center for Protein Research University of Copenhagen Copenhagen Denmark

8. Centre of Biological Engineering University of Minho ‐ Campus de Gualtar Braga Portugal

9. Department of Urology and Pediatric Urology St. Antonius Hospital Eschweiler Academic Teaching Hospital of RWTH Aachen Eschweiler Germany

10. Department of Urology and Kidney Transplantation Martin Luther University Halle (Saale) Germany

11. Department of Hematology Erasmus MC Rotterdam The Netherlands

12. Institute for Research and Innovation in Health (i3s) Porto Portugal

13. European Molecular Biology Laboratory European Bioinformatics Institute (EMBL‐EBI) Hinxton UK

14. Molecular Medicine Partnership Unit, European Molecular Biology Laboratory Heidelberg University Heidelberg Germany

Funder

Medical Research Council

Novo Nordisk Fonden

Lundbeckfonden

H2020 European Research Council

Publisher

EMBO

Subject

Applied Mathematics,Computational Theory and Mathematics,General Agricultural and Biological Sciences,General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,Information Systems

Link

https://onlinelibrary.wiley.com/doi/pdf/10.15252/msb.20209730

Reference67 articles.

1. Tumor Necrosis Factor Receptor Expression and Signaling in Renal Cell Carcinoma

2. Functional characterization of somatic mutations in cancer using network-based inference of protein activity

3. Epidermal growth factor receptor inhibition sensitizes renal cell carcinoma cells to the cytotoxic effects of bortezomib

4. Branched-chain amino acid metabolism in cancer

5. Multi‐Omics Factor Analysis—a framework for unsupervised integration of multi‐omics data sets

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