Newly Synthesized Micro-Nano Transition Metal Complexes of Hexadecanoic Acid as Anti-Microbial Agents: Synthesis, Characterization, and Biological Investigations

Abstract

The synthesis of several metal complexes of d-block elements of hexadecanoic acid (palmitic acid) and its antimicrobial activity was reported in this study. UV-Vis and FT-IR spectroscopy studies were used to characterize and confirm the produced metal complexes by the shift in the absorbance and the formation of M-O linkage. The X-ray diffraction method was mainly used to examine the crystallographic faces of the complexes based on the transition metals. Thermal gravimetric investigation revealed that all metal palmitate complexes had high thermal stability in the range of 250-300°C. The metal complexes of hexadecanoic acid were examined for microbicidal activity against diverse bacterial strains and fungal pathogens using the agar well diffusion method. The copper palmitate complex presented excellent antibacterial activity among the other metal complexes. These outcomes suggest of using fatty acid metal complexes as a suitable candidate in several biomedical applications.