Stem Cell Therapy and Exercise for Treatment of Intervertebral Disc Degeneration-Reference-Cited by-同舟云学术

Stem Cell Therapy and Exercise for Treatment of Intervertebral Disc Degeneration

Published:2021-10-13 Issue: Volume:2021 Page:1-10
ISSN:1687-9678
Container-title:Stem Cells International
language:en
Short-container-title:Stem Cells International

Author:

Li Bo¹,Yang Yunmei¹,Wang Lan¹,Liu Guanghua²^ORCID

Affiliation:

1. Department of Geriatrics, The First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, 310003 Zhejiang, China

2. Department of Rehabilitation Medicine, Zhongshan Hospital, Fudan University, Shanghai 200032, China

Abstract

As part of the motor system, intervertebral disc (IVD) is a complicated tissue with multiple components. The degeneration of IVD may result in low back pain (LBP), which strongly impairs quality of life. Various causes are related to the degeneration of IVD, including cell senescence, hydration lost, and inflammation. Stem cells founded in different tissues have attracted the interest of the researchers and clinicians to study the implication of these cells in the treatment for tissue injury and degeneration. In this report, we will review the study of stem cells in the treatment for IVD degeneration. On the other hand, the effect of exercise on IVD degeneration and the relationship between IVD degeneration and musculoskeletal disorders like sarcopenia are discussed.

Publisher

Hindawi Limited

Subject

Cell Biology,Molecular Biology

Link

http://downloads.hindawi.com/journals/sci/2021/7982333.pdf

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