Polymyxin B-Induced Skin Hyperpigmentation

Author:

Wen Xueke1,Luo Chunliu2ORCID,Lyu Weitao2

Affiliation:

1. The First Clinical Medical College of Jinan University, No. 601 Huangpu Avenue West, Guangzhou City 510630, Guangdong Province, China

2. The First Affiliated Hospital of Jinan University, No. 613 Huangpu Avenue West, Guangzhou City 510630, Guangdong Province, China

Abstract

Polymyxin B-induced skin hyperpigmentation is a rare adverse drug reaction (ADR). In this report, we present the case of a patient who underwent an abscess resection with right epididymitis, in which a multidrug-resistant Klebsiella pneumoniae infection (KPI) is formed. The patient was treated with polymyxin B and subsequently developed skin hyperpigmentation and desquamation. The desquamation improved and the pigmentation gradually returned to normal after sixty days after the withdrawal of polymyxin B.

Publisher

Hindawi Limited

Subject

General Medicine

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