Successful Treatment of Chronic Mucocutaneous Candidiasis Caused by Azole-ResistantCandida albicanswith Posaconazole-Reference-Cited by-同舟云学术

Successful Treatment of Chronic Mucocutaneous Candidiasis Caused by Azole-ResistantCandida albicanswith Posaconazole

Published:2011 Issue: Volume:2011 Page:1-4
ISSN:1740-2522
Container-title:Clinical and Developmental Immunology
language:en
Short-container-title:Clinical and Developmental Immunology

Author:

Firinu Davide¹^ORCID,Massidda Orietta²^ORCID,Lorrai Maria Maddalena¹,Serusi Loredana¹,Peralta Monica¹,Barca Maria Pina¹,Serra Paolo¹,Manconi Paolo Emilio¹

Affiliation:

1. Department of Internal Medicine, Allergy and Clinical Immunology, Azienda Ospedaliero Universitaria, University of Cagliari, SS 554- Bivio Sestu, 09042 Monserrato, Cagliari, Italy

2. Department of Biomedical Sciences and Technologies, Medical Microbiology, University of Cagliari, 09100 Cagliari, Italy

Abstract

Refractory or recurrent infections of skin, nails, and the mucous membranes are clinical signs of chronic mucocutaneous candidiasis, frequently associated with immunological defects. Here we describe a 39-years-old female patient, with familial CMC, that presented with an extensive infection caused by an azole-resistantCandida albicansisolate, successfully treated with posaconazole.

Publisher

Hindawi Limited

Subject

General Medicine,Immunology,Immunology and Allergy

Link

http://downloads.hindawi.com/journals/jir/2011/283239.pdf

Reference20 articles.

1. Chronic mucocutaneous candidiasis

2. Dominant-negative mutations in the DNA-binding domain of STAT3 cause hyper-IgE syndrome

3. Reduction of fluconazole susceptibility of Candida albicans in APECED patients due to long-term use of ketoconazole and miconazole

4. A common mutation in Sardinian autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients

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