Affiliation:
1. United States Food and Drug Administration, Center for Biologics Evaluation and Research, Silver Spring, MD 20993, USA
Abstract
Dengue is the most important reemerging mosquito-borne viral disease worldwide. It is caused by any of fourDengue virustypes or serotypes (DENV-1 to DENV-4) and is transmitted by mosquitoes from the genusAedes. Ecological changes have favored the geographic expansion of the vector and, since the dengue pandemic in the Asian and Pacific regions, the infection became widely distributed worldwide, reaching Brazil in 1845. The incidence of dengue in Brazil has been frequently high, and the number of cases in the country has at some point in time represented up to 60% of the dengue reported cases worldwide. This review addresses vector distribution, dengue outbreaks, circulating serotypes and genotypes, and prevention approaches being utilized in Brazil.
Subject
General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine
Cited by
89 articles.
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