Current Approach in the Diagnosis and Management of Uveitic Glaucoma

Author:

Muñoz-Negrete Francisco J.123,Moreno-Montañés Javier34,Hernández-Martínez Paula1,Rebolleda Gema123

Affiliation:

1. Ophthalmology Service, Hospital Universitario Ramón y Cajal, Instituto Ramón y Cajal de Investigaciones Sanitarias (IRYCIS), Madrid, Spain

2. Universidad de Alcalá, Alcalá de Henares, Spain

3. Ocular Pathology National Net (OFTARED) of the Institute of Health Carlos III, Madrid, Spain

4. Department of Ophthalmology, Clínica Universidad de Navarra, Pamplona, Spain

Abstract

Uveitic glaucoma (UG) typically is associated with very high intraocular pressure (IOP) and more intense optic nerve damage than other glaucoma types. This secondary glaucoma requires an early diagnosis and adequate management of both uveitis and glaucoma. It is mandatory to identify the mechanisms of IOP elevation that in many eyes have multiple combined mechanisms. Management of these patients commonly requires an interdisciplinary approach that includes a glaucoma specialist and rheumatologist to control the inflammation and IOP. Glaucoma surgery is required early in these patients due to the high IOP usually present and is less successful than in primary open-angle glaucoma. Recurrent uveitic episodes, multiple mechanism, and the complications associated with uveitis make surgical management of UG challenging. In this review, the management and treatment of UG are updated to clarify the pathogenesis and prevent optic nerve damage.

Funder

Spanish Ministry of Economy and Competitiveness

Publisher

Hindawi Limited

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

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