Traditional Medicinal Plants as a Source of Antituberculosis Drugs: A System Review

Author:

Xu Yuhui1,Liang Bowen2,Kong Chengcheng34,Sun Zhaogang34ORCID

Affiliation:

1. Institute of Chinese Materia Medica, China Academy of Chinese Medical Science, Beijing 100700, China

2. Department of Traditional Chinese Medicine, Beijing Chest Hospital, Capital Medical University, Beijing 101149, China

3. Translational Medicine Center, Beijing Chest Hospital, Capital Medical University, Beijing 101149, China

4. Beijing Key Laboratory in Drug Resistant Tuberculosis Research, Beijing Tuberculosis & Thoracic Tumor Research Institute, Beijing 101149, China

Abstract

Medicinal plants are the chief components in the different oriental formulations in different traditional medical systems worldwide. As a thriving source of medicine, the medicinal plants with antituberculosis (TB) properties inspire the pharmacists to develop new drugs based on their active components or semimetabolites. In the present review, the anti-TB medicinal plants were screened from the scientific literatures, based on the botanical classification and the anti-TB activity. The obtained anti-TB medicinal plants were categorized into three different categories, viz., 159 plants critically examined with a total 335 isolated compounds, 131 plants with their crude extracts showing anti-TB activity, and 27 plants in literature with the prescribed formula by the traditional healers. Our systemic analysis on the medicinal plants can assist the discovery of novel and more efficacious anti-TB drugs.

Funder

Beijing Municipal Natural Science Foundation

Publisher

Hindawi Limited

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

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