Implications of Green Tea and Its Constituents in the Prevention of Cancer via the Modulation of Cell Signalling Pathway

Author:

Rahmani Arshad H.1,Al shabrmi Fahad M.1,Allemailem Khaled S.1,Aly Salah M.12,Khan Masood A.3

Affiliation:

1. Department of Medical Laboratories, College of Applied Medical Sciences, Qassim University, Buraidah 6699, Saudi Arabia

2. Department of Pathology, Faculty of Veterinary Medicine, Suez Canal University, Ismailia, Egypt

3. Department of Basic Health Science, College of Applied Medical Sciences, Qassim University, Buraidah 6699, Saudi Arabia

Abstract

Green tea is commonly used as a beverage worldwide, especially in China, Japan, Morocco, and Saudi Arabia. Green tea and its constituents have been considered very effective in the prevention and treatment of various diseases. It contains a variety of catechins, which show a pivotal role in the modulation of biological activities and also act as chemopreventive agents. Earlier studies have confirmed that green tea and its chief constituent epigallocatechin gallate (EGCG) have a potential role in the management of cancer through the modulation of cell signaling pathways. In this review, we focused on the beneficial effects of green tea and its constituents in the cancer prevention and treatment and its impact on modulation of molecular pathways.

Publisher

Hindawi Limited

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

Reference109 articles.

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