Menthol Toxicity: An Unusual Cause of Coma

Author:

Baibars Motaz1,Eng Simona1,Shaheen Khaldoon2ORCID,Alraiyes Abdul Hamid3,Alraies M. Chadi4ORCID

Affiliation:

1. Hospital Medicine/Internal Medicine Department, Peninsula Regional Medical Center, Salisbury, MD 2180, USA

2. Department of Hospital Medicine, Cleveland Clinic, Cleveland, OH 44195, USA

3. Department of Pulmonary, Critical Care and Environmental Medicine, Tulane University Health Sciences Center, New Orleans, LA 70112, USA

4. Cleveland Clinic Lerner College of Medicine of Case Western Reserve University and Department of Hospital Medicine Institute, Cleveland Clinic, 9500 Euclid Avenue, Mail Code A13, Cleveland, OH 44195, USA

Abstract

The US Food and Drug Administration (FDA) consider menthol an effective substance, which help in common cold symptoms and labeled to have low toxicity profile. Direct exposure to high menthol amount has been reported in animal; but no studies have been done to show the effect of menthol on long-term use in humans. Up to our knowledge we are reporting a rare case of chronic exposure to significant amount of menthol associated with cutaneous, gastrointestinal and neurological manifestations.

Publisher

Hindawi Limited

Subject

General Medicine

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