Donor Cell Myeloid Sarcoma in an Umbilical Cord Transplant Patient: A Case Report and a Review of the Literature-Reference-Cited by-同舟云学术

Donor Cell Myeloid Sarcoma in an Umbilical Cord Transplant Patient: A Case Report and a Review of the Literature

Published:2015 Issue: Volume:2015 Page:1-4
ISSN:2090-6560
Container-title:Case Reports in Hematology
language:en
Short-container-title:Case Reports in Hematology

Author:

Hayes Christi¹,Petersen Bruce²,Malone Adriana³

Affiliation:

1. Department of Hematology, Norris Cotton Cancer Center, Dartmouth-Hitchcock Medical Center, Lebanon, NH 03756, USA

2. Department of Pathology, Mount Sinai Medical Center, New York, NY 10029, USA

3. Bone Marrow and Stem Cell Transplantation, Icahn School of Medicine at Mount Sinai, New York, NY, USA

Abstract

Donor cell leukemia (DCL) represents a rare complication of allogeneic transplantation. The precise incidence remains unclear, though it may be higher following umbilical cord blood transplants. Here, we present an unusual case of a patient with B-ALL who presented with a donor derived myeloid sarcoma of the heart following a double cord blood transplant. To our knowledge, it is the first case of sarcomatous or chloromatous presentation of DCL following a UCBT.

Publisher

Hindawi Limited

Subject

Cell Biology,Developmental Biology,Embryology,Anatomy

Link

http://downloads.hindawi.com/journals/crihem/2015/186869.pdf

Reference12 articles.

1. LEUKÆMIC TRANSFORMATION OF ENGRAFTED HUMAN MARROW CELLS IN VIVO

2. First report of donor cell–derived acute leukemia as a complication of umbilical cord blood transplantation

3. Donor cell derived acute myeloid leukemia after allogeneic cord blood transplantation in a patient with adult T-cell lymphoma

4. Four cases of donor cell-derived AML following unrelated cord blood transplantation for adult patients: experiences of the Tokyo Cord Blood Bank

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