Production, Transmission, Pathogenesis, and Control of Dengue Virus: A Literature-Based Undivided Perspective

Author:

Islam Muhammad Torequl1,Quispe Cristina2,Herrera-Bravo Jesús34ORCID,Sarkar Chandan1,Sharma Rohit5ORCID,Garg Neha6,Fredes Larry Ibarra7,Martorell Miquel89ORCID,Alshehri Mohammed M.10ORCID,Sharifi-Rad Javad11ORCID,Daştan Sevgi Durna1213,Calina Daniela14ORCID,Alsafi Radi15ORCID,Alghamdi Saad15ORCID,Batiha Gaber El-Saber16,Cruz-Martins Natália171819ORCID

Affiliation:

1. Department of Pharmacy, Life Science Faculty, Bangabandhu Sheikh Mujibur Rahman Science and Technology University, Gopalganj (Dhaka)8100, Bangladesh

2. Facultad de Ciencias de la Salud, Universidad Arturo Prat, Avda. Arturo Prat 2120, Iquique 1110939, Chile

3. Departamento de Ciencias Básicas, Facultad de Ciencias, Universidad Santo Tomas, Chile

4. Center of Molecular Biology and Pharmacogenetics, Scientific and Technological Bioresource Nucleus, Universidad de La Frontera, Temuco 4811230, Chile

5. Department of Rasa Shastra & Bhaishajya Kalpana, Faculty of Ayurveda, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, Uttar Pradesh, India

6. Department of Medicinal Chemistry, Institute of Medical Sciences, Banaras Hindu University, Varanasi-221005, Uttar Pradesh, India

7. European Institute of Traditional Chinese Studies, 4000-501 Porto, Portugal

8. Department of Nutrition and Dietetics, Faculty of Pharmacy, and Centre for Healthy Living, University of Concepción, 4070386 Concepción, Chile

9. Universidad de Concepción, Unidad de Desarrollo Tecnológico, UDT, Concepción 4070386, Chile

10. Pharmaceutical Care Department, Ministry of National Guard-Health Affairs, Riyadh, Saudi Arabia

11. Facultad de Medicina, Universidad del Azuay, Cuenca, Ecuador

12. Department of Biology, Faculty of Science, Sivas Cumhuriyet University, 58140 Sivas, Turkey

13. Beekeeping Development Application and Research Center, Sivas Cumhuriyet University, 58140 Sivas, Turkey

14. Department of Clinical Pharmacy, University of Medicine and Pharmacy of Craiova, 200349 Craiova, Romania

15. Laboratory Medicine Department, Faculty of Applied Medical Sciences, Umm Al-Qura University, Makkah, Saudi Arabia

16. Department of Pharmacology and Therapeutics, Faculty of Veterinary Medicine, Damanhour University, Damanhour, Egypt

17. Faculty of Medicine, University of Porto, Porto, Portugal

18. Institute for Research and Innovation in Health (i3S), University of Porto, Porto, Portugal

19. Institute of Research and Advanced Training in Health Sciences and Technologies (CESPU), Rua Central de Gandra, 1317, 4585-116 Gandra PRD, Portugal

Abstract

Dengue remains one of the most serious and widespread mosquito-borne viral infections in human beings, with serious health problems or even death. About 50 to 100 million people are newly infected annually, with almost 2.5 billion people living at risk and resulting in 20,000 deaths. Dengue virus infection is especially transmitted through bites of Aedes mosquitos, hugely spread in tropical and subtropical environments, mostly found in urban and semiurban areas. Unfortunately, there is no particular therapeutic approach, but prevention, adequate consciousness, detection at earlier stage of viral infection, and appropriate medical care can lower the fatality rates. This review offers a comprehensive view of production, transmission, pathogenesis, and control measures of the dengue virus and its vectors.

Funder

CONICYT PIA/APOYO CCTE

Publisher

Hindawi Limited

Subject

General Immunology and Microbiology,General Biochemistry, Genetics and Molecular Biology,General Medicine

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