A Case of Cryptogenic Organizing Pneumonia Occurring in Crohn’s Disease

Author:

Carratù Pierluigi1,Dragonieri Silvano1,Nocerino Maria Cristina1,Trabucco Senia Maria Rosaria2,Lacedonia Donato1,Parisi Giuseppe2,Resta Onofrio1

Affiliation:

1. Institute of Respiratory Disease, Department of Clinical Methodology and Medical Surgery Technology, Italy

2. Institute of Pathological Anatomy, University of Bari, Bari, Italy

Abstract

A 29 year-old-man with Crohn's disease, who developed diffuse pulmonary infiltrates and hypoxemia two months following oral administration of mesalazine, was examined. Clinical findings and computed tomography were suggestive of, and lung histology was diagnostic of, bronchiolitis obliterans organizing pneumonia, also known as cryptogenic organizing pneumonia. Although the data did not allow for definitive conclusions, they did suggest that the pulmonary disease was an extraintestinal manifestation of Crohn's disease, rather than an adverse reaction to mesalazine. In fact, the patient showed clinical, radiological and functional improvements, despite the treatment with mesalazine and the withdrawal of steroid therapy.

Publisher

Hindawi Limited

Subject

Pulmonary and Respiratory Medicine

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