Helicobacter pylori: Determinant and Markers of Virulence

Abstract

In this review, we examine the main virulence determinants inHelicobacter pylori(Hp) strains and the correlation between these and the different diseases followingHpinfections. We also discuss the host response toHpand the implications and advantages of the development of non-invasive pre-endoscopy screening of molecular and serological markers associated withHpvirulence and disease progression putting an emphasis on new screening techniques such as the Luminex – X multi analytes profiling technology and the multiplex PCR.