Affiliation:
1. Somov Institute of Epidemiology and Microbiology
2. Far Eastern Federal University
3. Medical Association of the Far Eastern Branch of the Russian Academy of Sciences
4. G. B. Elyakov Pacific Institute of Bioorganic Chemistry
Abstract
According to epidemiological data, 60% of the world's population suffers fromHelicobacterpyloriinfection. The multicomponent treatment used in 18–20% of cases does not allow eradication ofH.pylori. In addition, reinfection withH.pylorioccurs in the majority of treated patients in 3–5 years. An alternative to antibiotics in the treatment of this infection are seaweed products, in particular extracts and polysaccharides with anti-adhesive, anti-toxic, immunomodulatory, antioxidant, and anti-inflammatory properties. Furthermore, algae polysaccharides have direct bactericidal effect and can destroy biofilms formed byH.pylori. The modern materials presented in the literature review indicate the prospects of developments related to the use of extracts and polysaccharides from seaweed as the basis for drugs, dietary supplements and functional food products for the prevention and treatment ofH.pyloriinfection.
Subject
Infectious Diseases,Microbiology (medical),General Medicine,Microbiology
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