Affiliation:
1. Units of Infectology and Dermatology, Department of Internal Medicine, National University of Colombia, 111321 Bogotá, Colombia
Abstract
Toxic epidermal necrolysis is the most severe form of drug-induced skin reaction and includes denudation of >30% of total body surface area. The mechanism of disease is not completely understood, but immunologic mechanisms, cytotoxic reactions, and delayed hypersensitivity seem to be involved. We report a case of cephazolin-induced toxic epidermal necrolysis treated with intravenous immunoglobulin and N-acetylcysteine with excellent response.
Subject
Immunology,Immunology and Allergy
Cited by
8 articles.
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