Commercially Available Textiles as a Scaffolding Platform for Large-Scale Cell Culture

Author:

Agarwal Tarun12ORCID,Tan Sheri-Ann3ORCID,Rathnam Vuppaladadium Shanmuga Sharan4ORCID,Sajja Tanmayi2ORCID,Maiti Tapas Kumar1ORCID

Affiliation:

1. Department of Biotechnology, Indian Institute of Technology, Kharagpur, West Bengal-721302, India

2. Department of Bio-Technology, Koneru Lakshmaiah Education Foundation, Vaddeswaram, AP, India

3. Department of Bioscience, Faculty of Applied Sciences, Tunku Abdul Rahman University of Management and Technology, Kuala Lumpur 53300, Malaysia

4. Department of Biotechnology and Medical Engineering, National Institute of Technology, Rourkela, Odisha, India

Abstract

The present study outlines the evaluation of textile materials that are currently in the market for cell culture applications. By using normal LaserJet printing techniques, we created the substrates, which were then characterized physicochemically and biologically. In particular, (i) we found that the weave pattern and (ii) the chemical nature of the textiles significantly influenced the behaviour of the cells. Textiles with closely knitted fibers and cell adhesion motifs, exhibited better cell adhesion and proliferation over a period of 7 days. All the substrates supported good viability of cells (>80%). We believe that these aspects make commercially available textiles as a potential candidate for large-scale culture of adherent cells.

Publisher

Hindawi Limited

Subject

Biomedical Engineering,Biomaterials

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