Synthesis and Biological Evaluation of New Hydrazone Derivatives of Quinoline and Their Cu(II) and Zn(II) Complexes againstMycobacterium tuberculosis-Reference-Cited by-同舟云学术

Synthesis and Biological Evaluation of New Hydrazone Derivatives of Quinoline and Their Cu(II) and Zn(II) Complexes againstMycobacterium tuberculosis

Published:2015 Issue: Volume:2015 Page:1-14
ISSN:1565-3633
Container-title:Bioinorganic Chemistry and Applications
language:en
Short-container-title:Bioinorganic Chemistry and Applications

Author:

Mandewale Mustapha C.¹,Thorat Bapu¹,Shelke Dnyaneshwar¹,Yamgar Ramesh²

Affiliation:

1. P.G. and Research Centre, Department of Chemistry, Government of Maharashtra, Ismail Yusuf College of Arts, Science and Commerce, Jogeshwari (East), Mumbai 400 060, India

2. Department of Chemistry, Chikitsak Samuha’s Patkar-Varde College of Arts, Science and Commerce, Goregaon (West), Mumbai 400 062, India

Abstract

A new series of quinoline hydrazone derivatives and their metal complexes have been synthesized and their biological properties have been evaluated againstMycobacterium tuberculosis(H37 RV strain). Most of the newly synthesized compounds displayed 100% inhibitory activity at a concentration of 6.25–25 μg/mL, againstMycobacterium tuberculosis. Fluorescence properties of all the synthesized compounds have been studied.

Publisher

Hindawi Limited

Subject

Inorganic Chemistry,Organic Chemistry,Biochemistry

Link

http://downloads.hindawi.com/journals/bca/2015/153015.pdf

Reference27 articles.

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2. Cavitary Disease and Quantitative Sputum Bacillary Load in Cases of Pulmonary Tuberculosis

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